This page contains trivia for "The Biggest Douche in the Universe". Remember, trivia must be factual, provable, and it is always best to cite your source for not-so-obvious trivia. If you would like to dispute a trivia point, please discuss it in the article comments.
Jewleeard is a parody of Juilliard School for the Arts in New York.
This episode is the second to show the Visitors interacting publicly with the other characters.
The airplane the boys fly to New York on is a McDonnell Douglas DC-9 (Series 10).
Chef's last name is spelled "McGilroy" on the name tag the ham is on.
The Rob Schneider trailers reference the 2002 movie The Hot Chick, which came out on December 13, 2002, two weeks after this episode aired.
Stan speaks in monotone for most of the episode.
The primary plotline of Kenny possessing Cartman is an allusion to the film Star Trek III: The Search For Spock, directed by Leonard Nimoy, as what happens to Cartman parallels what happened to McCoy when he held Spock's soul in his body.
John Edward is a medium, famous for having a talk show in syndication and a book called Crossing Over with John Edward.