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When the school bus becomes perilously trapped on the edge of a cliff, the driver Ms. Crabtree, searches for help. She finds the highway and hitch hikes a ride from a semi-truck driver, named Mitch, who resembles Elvis Presley in speech and mannerisms. Together they travel around the United States visiting comedy clubs and late night talk shows as Ms. Crabtree becomes a sensation in stand-up comedy.
- Roofies are street slang for animal tranquilizers used by veterinarians.
- Elvis Presley was a delivery truck driver before he became famous as a musician.