This page contains trivia for "Medicinal Fried Chicken". Remember, trivia must be factual, provable, and it is always best to cite your source for not-so-obvious trivia. If you would like to dispute a trivia point, please discuss it in the article comments.
The condition of Randy and the other men appears to be Elephantiasis of the scrotum rather than testicular cancer. Of course, the increased size is a humorous exaggeration of the tumors in their testicles.
Kenny has no lines and isn't shown again after they find out that KFC has been replaced. This is also the last time we see Kyle in this episode as well. (Stan is seen a few more times during the episode but only very briefly).
The scene with Randy trying to move after his balls fall out of the wheelbarrow was originally acted out by Trey using a large yoga ball. The animators took this video and animated it, almost frame-for-frame.
References to Popular Culture
Cartman makes numerous references to the March/April 2010 scandal in the Catholic Church that Pope Benedict XVI protected the priest that molested over 200 deaf boys, as well as other pedophile priests (which drew massive controversy).
This episode marks the fourth mention of KFC, but the second time in which KFC's importance to the boys is a driving story point.
Much of Cartman's story, and his relationship with Colonel Sanders, is a parody of assorted drug related films, most prominently Scarface.
Some scenes (especially when Cartman is talking to the Colonel in Corbin) are scene-for-scene recreations from the movie Scarface. Even most of the original lines (albeit spoken by Cartman and Sanders) are used.
KFC is used in a similar way to cocaine in the episode, from workers cutting it to Cartman chopping it with a credit card and snorting it.
British celebrity chef Jamie Oliver and his attempts at getting America to move onto healthier foods is mentioned. He appears again in "Crème Fraiche" with similar motives.