It appeared when the 'Pissed Off and Angry Party' broke into the FedEx Office because Randy Marsh thought that it was a federal building. They threaten the workers, but later leave when their penises are no longer declared short.
- In "Bass to Mouth", Wikileaks was seen sitting on a FedEx box.
- In "Cash For Gold", a FedEx truck was seen delivering Jewelry.
- In "Cartman Finds Love", a FedEx delivery man delivers to Kyle a pair tickets for the game of the Nuggets.
- In "Moss Piglets", a microscopic FedEx box is inserted onto a microscope, where the Water Bears become attracted to it.
- "T.M.I." - Seen when Pissed Off and Angry Party takes the building hostage.