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Annie, Anne or Ann may refer to one of the following:
- Anne Garefino - An executive producer for South Park.
- Annie - A girl who joined Butters' "kissing company" in "Butters' Bottom Bitch".
- Annie Bartlett- A female fifth grader in the South Park Vampire Society.
- Annie Knitts - A popular girl commonly seen in Wendy's circle of friends.
- Sister Ann - A Catholic nun who appeared in "Do the Handicapped Go to Hell?" and "Probably".